Aging-related endothelial dysfunction
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Aging is a major risk factor for the development of several cardiovascular diseases. Some cardiovascular diseases such as atherosclerosis or hypertension are accompanied by a decreased endothelial function. Age-related endothelial dysfunction affects the balance between vasodilator and vasoconstriction substances in the endothelium. In addition, oxidative stress and inflammation seem to be the primary causes of age-related endothelial dysfunction.